Design, Synthesis and Biological Evaluation of 6-(Imidazo[1,2-a]pyridin-6-yl)quinazoline Derivatives as Anticancer Agents via PI3Kα Inhibition

Aberrant expression of the phosphatidylinositol 3-kinase (PI3K) signalling pathway is often associated with tumourigenesis, progression and poor prognosis. Hence, PI3K inhibitors have attracted significant interest for the treatment of cancer. In this study, a series of new 6-(imidazo[1,2-a]pyridin-...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Mei, Wang, Daoping, Li, Qing, Luo, Fang, Zhong, Ting, Wu, Hongshan, Xiong, Liang, Yuan, Meitao, Su, Mingzhi, Fan, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095550/
https://www.ncbi.nlm.nih.gov/pubmed/37047827
http://dx.doi.org/10.3390/ijms24076851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095550/
https://www.ncbi.nlm.nih.gov/pubmed/37047827
http://dx.doi.org/10.3390/ijms24076851

Ejemplares similares