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Design, Synthesis and Biological Evaluation of 6-(Imidazo[1,2-a]pyridin-6-yl)quinazoline Derivatives as Anticancer Agents via PI3Kα Inhibition

Aberrant expression of the phosphatidylinositol 3-kinase (PI3K) signalling pathway is often associated with tumourigenesis, progression and poor prognosis. Hence, PI3K inhibitors have attracted significant interest for the treatment of cancer. In this study, a series of new 6-(imidazo[1,2-a]pyridin-...

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Detalles Bibliográficos
Autores principales:	Li, Mei, Wang, Daoping, Li, Qing, Luo, Fang, Zhong, Ting, Wu, Hongshan, Xiong, Liang, Yuan, Meitao, Su, Mingzhi, Fan, Yanhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095550/ https://www.ncbi.nlm.nih.gov/pubmed/37047827 http://dx.doi.org/10.3390/ijms24076851

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