Persistent Lipid Accumulation Leads to Persistent Exacerbation of Endoplasmic Reticulum Stress and Inflammation in Progressive NASH via the IRE1α/TRAF2 Complex

Non-alcoholic steatohepatitis (NASH) is a metabolic disorder that often leads to other severe liver diseases, yet treatment options are limited. Endoplasmic reticulum (ER) stress is an important pathogenetic mechanism of NASH and plays a key role in tandem steatosis as well as liver inflammation. Th...

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Detalles Bibliográficos
Autores principales: Lei, Na, Song, Hongfei, Zeng, Ling, Ji, Shaoxiu, Meng, Xiangbo, Zhu, Xiuying, Li, Xiuyan, Feng, Quansheng, Liu, Jibin, Mu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095702/
https://www.ncbi.nlm.nih.gov/pubmed/37049952
http://dx.doi.org/10.3390/molecules28073185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095702/
https://www.ncbi.nlm.nih.gov/pubmed/37049952
http://dx.doi.org/10.3390/molecules28073185

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