Regioselective Cyclic Iminium Formation of Ugi Advanced Intermediates: Rapid Access to 3,4-Dihydropyrazin-2(1H)-ones and Other Diverse Nitrogen-Containing Heterocycles

Herein, advanced intermediates were synthesized through Ugi four-component reactions of isocyanides, aldehydes, masked amino aldehyde, and carboxylic acids, including N-protected amino acids. The presence of a masked aldehyde enabled acid-mediated deprotection and subsequent cyclization via the carb...

Descripción completa

Detalles Bibliográficos
Autores principales: Cankařová, Naděžda, Krchňák, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095709/
https://www.ncbi.nlm.nih.gov/pubmed/37049824
http://dx.doi.org/10.3390/molecules28073062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095709/
https://www.ncbi.nlm.nih.gov/pubmed/37049824
http://dx.doi.org/10.3390/molecules28073062

Ejemplares similares