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Uncarboxylated Osteocalcin Decreases SCD1 by Activating AMPK to Alleviate Hepatocyte Lipid Accumulation

Uncarboxylated osteocalcin (GluOC), a small-molecule protein specifically synthesized and secreted by osteoblasts, is important in the regulation of energy metabolism. In our previous study, GluOC was shown to be effective in ameliorating dyslipidemia and hepatic steatosis in KKAy mice. However, the...

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Detalles Bibliográficos
Autores principales: Wang, Danqing, Zhang, Miao, Xu, Jiaojiao, Yang, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095730/
https://www.ncbi.nlm.nih.gov/pubmed/37049884
http://dx.doi.org/10.3390/molecules28073121