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One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams

The Friedel–Crafts reaction of novel 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones was used for low cost, one-pot preparation of polycyclic indole derivatives structurally similar to Ergot alkaloids.

Detalles Bibliográficos
Autores principales: Abaev, Vladimir T., Aksenov, Nicolai A., Aksenov, Dmitrii A., Aleksandrova, Elena V., Akulova, Alesia S., Kurenkov, Igor A., Leontiev, Alexander V., Aksenov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095734/
https://www.ncbi.nlm.nih.gov/pubmed/37049924
http://dx.doi.org/10.3390/molecules28073162