One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams

The Friedel–Crafts reaction of novel 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones was used for low cost, one-pot preparation of polycyclic indole derivatives structurally similar to Ergot alkaloids.

Detalles Bibliográficos
Autores principales: Abaev, Vladimir T., Aksenov, Nicolai A., Aksenov, Dmitrii A., Aleksandrova, Elena V., Akulova, Alesia S., Kurenkov, Igor A., Leontiev, Alexander V., Aksenov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095734/
https://www.ncbi.nlm.nih.gov/pubmed/37049924
http://dx.doi.org/10.3390/molecules28073162
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author Abaev, Vladimir T.
Aksenov, Nicolai A.
Aksenov, Dmitrii A.
Aleksandrova, Elena V.
Akulova, Alesia S.
Kurenkov, Igor A.
Leontiev, Alexander V.
Aksenov, Alexander V.
author_facet Abaev, Vladimir T.
Aksenov, Nicolai A.
Aksenov, Dmitrii A.
Aleksandrova, Elena V.
Akulova, Alesia S.
Kurenkov, Igor A.
Leontiev, Alexander V.
Aksenov, Alexander V.
author_sort Abaev, Vladimir T.
collection PubMed
description The Friedel–Crafts reaction of novel 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones was used for low cost, one-pot preparation of polycyclic indole derivatives structurally similar to Ergot alkaloids.
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spelling pubmed-100957342023-04-13 One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams Abaev, Vladimir T. Aksenov, Nicolai A. Aksenov, Dmitrii A. Aleksandrova, Elena V. Akulova, Alesia S. Kurenkov, Igor A. Leontiev, Alexander V. Aksenov, Alexander V. Molecules Article The Friedel–Crafts reaction of novel 3,5-diarylsubstituted 5-hydroxy-1,5-dihydro-2H-pyrrol-2-ones was used for low cost, one-pot preparation of polycyclic indole derivatives structurally similar to Ergot alkaloids. MDPI 2023-04-02 /pmc/articles/PMC10095734/ /pubmed/37049924 http://dx.doi.org/10.3390/molecules28073162 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Abaev, Vladimir T.
Aksenov, Nicolai A.
Aksenov, Dmitrii A.
Aleksandrova, Elena V.
Akulova, Alesia S.
Kurenkov, Igor A.
Leontiev, Alexander V.
Aksenov, Alexander V.
One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams
title One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams
title_full One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams
title_fullStr One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams
title_full_unstemmed One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams
title_short One-Pot Synthesis of Polynuclear Indole Derivatives by Friedel–Crafts Alkylation of γ-Hydroxybutyrolactams
title_sort one-pot synthesis of polynuclear indole derivatives by friedel–crafts alkylation of γ-hydroxybutyrolactams
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095734/
https://www.ncbi.nlm.nih.gov/pubmed/37049924
http://dx.doi.org/10.3390/molecules28073162
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