Modulatory Effects of Atractylodin and β-Eudesmol on Human Cytochrome P450 Enzymes: Potential Drug-Drug Interactions

Atractylodin and β-eudesmol, the major bioactive compounds in Atractylodes lancea, are promising candidates for anti-cholangiocarcinoma. The inhibitory effects of both compounds on human rCYP1A2, rCYP2C9, rCYP2C19, rCYP2D6 and rCYP3A4 enzymes were investigated using luminogenic CYP450 kits. The modu...

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Detalles Bibliográficos
Autores principales: Thiengsusuk, Artitaya, Plengsuriyakarn, Tullayakorn, Na-Bangchang, Kesara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095747/
https://www.ncbi.nlm.nih.gov/pubmed/37049902
http://dx.doi.org/10.3390/molecules28073140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095747/
https://www.ncbi.nlm.nih.gov/pubmed/37049902
http://dx.doi.org/10.3390/molecules28073140

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