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Molecular Modelling Study and Antibacterial Evaluation of Diphenylmethane Derivatives as Potential FabI Inhibitors

The need for new antibiotics has become a major worldwide challenge as bacterial strains keep developing resistance to the existing drugs at an alarming rate. Enoyl-acyl carrier protein reductases (FabI) play a crucial role in lipids and fatty acid biosynthesis, which are essential for the integrity...

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Detalles Bibliográficos
Autores principales: Hasan, Shaima, Kayed, Kawthar, Ghemrawi, Rose, Bataineh, Nezar Al, Mahgoub, Radwa E., Audeh, Rola, Aldulaymi, Raghad, Atatreh, Noor, Ghattas, Mohammad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095751/
https://www.ncbi.nlm.nih.gov/pubmed/37049763
http://dx.doi.org/10.3390/molecules28073000