Cargando…
Molecular Modelling Study and Antibacterial Evaluation of Diphenylmethane Derivatives as Potential FabI Inhibitors
The need for new antibiotics has become a major worldwide challenge as bacterial strains keep developing resistance to the existing drugs at an alarming rate. Enoyl-acyl carrier protein reductases (FabI) play a crucial role in lipids and fatty acid biosynthesis, which are essential for the integrity...
Autores principales: | Hasan, Shaima, Kayed, Kawthar, Ghemrawi, Rose, Bataineh, Nezar Al, Mahgoub, Radwa E., Audeh, Rola, Aldulaymi, Raghad, Atatreh, Noor, Ghattas, Mohammad A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095751/ https://www.ncbi.nlm.nih.gov/pubmed/37049763 http://dx.doi.org/10.3390/molecules28073000 |
Ejemplares similares
-
The Discovery of Potent SHP2 Inhibitors with Anti-Proliferative Activity in Breast Cancer Cell Lines
por: Ghemrawi, Rose, et al.
Publicado: (2022) -
Mutations upstream of fabI in triclosan resistant Staphylococcus aureus strains are associated with elevated fabI gene expression
por: Grandgirard, Denis, et al.
Publicado: (2015) -
Nonactive-Site Mutations in S. aureus FabI That Induce Triclosan Resistance
por: Demissie, Robel, et al.
Publicado: (2020) -
Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens
por: Parker, Erica N., et al.
Publicado: (2019) -
Mobile Phones: Reservoirs of Resistant Bacteria during the COVID-19 Pandemic in Abu Dhabi, United Arab Emirates
por: Kayed, Kawthar, et al.
Publicado: (2023)