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Discovery, Antitumor Activity, and Fermentation Optimization of Roquefortines from Penicillium sp. OUCMDZ-1435

Meleagrin and oxaline, which belong to the roquefortine alkaloids with a unique dihydroindole spiroamide framework, have significant bioactivities, especially tumor cell inhibitory activity. In order to discover the requefortine alkaloids, Penicillium sp. OUCMDZ-1435 was fished and identified from m...

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Detalles Bibliográficos
Autores principales: He, Xingxing, Jin, Yanzheng, Kong, Fei, Yang, Liyuan, Zhu, Mingzhuang, Wang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095773/
https://www.ncbi.nlm.nih.gov/pubmed/37049942
http://dx.doi.org/10.3390/molecules28073180