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MethylScore, a pipeline for accurate and context-aware identification of differentially methylated regions from population-scale plant whole-genome bisulfite sequencing data

Whole-genome bisulfite sequencing (WGBS) is the standard method for profiling DNA methylation at single-nucleotide resolution. Different tools have been developed to extract differentially methylated regions (DMRs), often built upon assumptions from mammalian data. Here, we present MethylScore, a pi...

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Detalles Bibliográficos
Autores principales: Hüther, Patrick, Hagmann, Jörg, Nunn, Adam, Kakoulidou, Ioanna, Pisupati, Rahul, Langenberger, David, Weigel, Detlef, Johannes, Frank, Schultheiss, Sebastian J., Becker, Claude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095865/
https://www.ncbi.nlm.nih.gov/pubmed/37077980
http://dx.doi.org/10.1017/qpb.2022.14