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Detailed Experimental and In Silico Investigation of Indomethacin Binding with Human Serum Albumin Considering Primary and Secondary Binding Sites

The interaction of indomethacin with human serum albumin (HSA) has been studied here considering the primary and secondary binding sites. The Stern–Volmer plots were linear in the lower concentration range of indomethacin while a downward curvature was observed in the higher concentration range, sug...

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Detalles Bibliográficos
Autores principales: Ali, Mohd Sajid, Muthukumaran, Jayaraman, Jain, Monika, Tariq, Mohammad, Al-Lohedan, Hamad A., Al-Sanea, Abdullah Saad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095894/
https://www.ncbi.nlm.nih.gov/pubmed/37049745
http://dx.doi.org/10.3390/molecules28072979