Compound 275# Induces Mitochondria-Mediated Apoptosis and Autophagy Initiation in Colorectal Cancer Cells through an Accumulation of Intracellular ROS

Colorectal cancer (CRC) is the most common intestinal malignancy, and nearly 70% of patients with this cancer develop metastatic disease. In the present study, we synthesized a novel compound, termed N-(3-(5,7-dimethylbenzo [d]oxazol-2-yl)phenyl)-5-nitrofuran-2-carboxamide (compound 275#), and found...

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Detalles Bibliográficos
Autores principales: Yang, Dong-Lin, Li, Yong, Ma, Shui-Qing, Zhang, Ya-Jun, Huang, Jiu-Hong, He, Liu-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095895/
https://www.ncbi.nlm.nih.gov/pubmed/37049976
http://dx.doi.org/10.3390/molecules28073211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095895/
https://www.ncbi.nlm.nih.gov/pubmed/37049976
http://dx.doi.org/10.3390/molecules28073211

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