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Compound 275# Induces Mitochondria-Mediated Apoptosis and Autophagy Initiation in Colorectal Cancer Cells through an Accumulation of Intracellular ROS
Colorectal cancer (CRC) is the most common intestinal malignancy, and nearly 70% of patients with this cancer develop metastatic disease. In the present study, we synthesized a novel compound, termed N-(3-(5,7-dimethylbenzo [d]oxazol-2-yl)phenyl)-5-nitrofuran-2-carboxamide (compound 275#), and found...
Autores principales: | Yang, Dong-Lin, Li, Yong, Ma, Shui-Qing, Zhang, Ya-Jun, Huang, Jiu-Hong, He, Liu-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095895/ https://www.ncbi.nlm.nih.gov/pubmed/37049976 http://dx.doi.org/10.3390/molecules28073211 |
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