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Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development Approach

An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several transcriptome servers were used to measure the differential expression of the targeted MDM2 gene and search mutations and co...

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Detalles Bibliográficos
Autores principales: Biswas, Partha, Bibi, Shabana, Yousafi, Qudsia, Mehmood, Asim, Saleem, Shahzad, Ihsan, Awais, Dey, Dipta, Hasan Zilani, Md. Nazmul, Hasan, Md. Nazmul, Saleem, Rasha, Awaji, Aeshah A., Fahmy, Usama A., Abdel-Daim, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095937/
https://www.ncbi.nlm.nih.gov/pubmed/37049742
http://dx.doi.org/10.3390/molecules28072977