One-Pot Phosphonylation of Heteroaromatic Lithium Reagents: The Scope and Limitations of Its Use for the Synthesis of Heteroaromatic Phosphonates

A one-pot lithiation–phosphonylation procedure was elaborated as a method to prepare heteroaromatic phosphonic acids. It relied on the direct lithiation of heteroaromatics followed by phosphonylation with diethyl chlorophosphite and then oxidation with hydrogen peroxide. This protocol provided the d...

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Detalles Bibliográficos
Autores principales: Chmielewska, Ewa, Miodowska, Natalia, Dziuk, Błażej, Psurski, Mateusz, Kafarski, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095984/
https://www.ncbi.nlm.nih.gov/pubmed/37049896
http://dx.doi.org/10.3390/molecules28073135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095984/
https://www.ncbi.nlm.nih.gov/pubmed/37049896
http://dx.doi.org/10.3390/molecules28073135

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