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A Brief Review on the Synthesis of the N-CF(3) Motif in Heterocycles
The trifluoromethyl group is widely recognized for its significant role in the fields of medicinal chemistry and material science due to its unique electronic and steric properties that can alter various physiochemical properties of the parent molecule, such as lipophilicity, acidity, and hydrogen b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10095997/ https://www.ncbi.nlm.nih.gov/pubmed/37049775 http://dx.doi.org/10.3390/molecules28073012 |