[3+3]-Annulation of Cyclic Nitronates with Vinyl Diazoacetates: Diastereoselective Synthesis of Partially Saturated [1,2]Oxazino[2,3-b][1,2]oxazines and Their Base-Promoted Ring Contraction to Pyrrolo[1,2-b][1,2]oxazine Derivatives

A rhodium(II)-catalyzed reaction of cyclic nitronates (5,6-dihydro-4H-1,2-oxazine N-oxides) with vinyl diazoacetates proceeds as a [3+3]-annulation producing bicyclic unsaturated nitroso acetals (4a,5,6,7-tetrahydro-2H-[1,2]oxazino[2,3-b][1,2]oxazines). Optimization of reaction conditions revealed t...

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Detalles Bibliográficos
Autores principales: Antonova, Yulia A., Nelyubina, Yulia V., Ioffe, Sema L., Tabolin, Andrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096057/
https://www.ncbi.nlm.nih.gov/pubmed/37049788
http://dx.doi.org/10.3390/molecules28073025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096057/
https://www.ncbi.nlm.nih.gov/pubmed/37049788
http://dx.doi.org/10.3390/molecules28073025

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