Rational Design and Lead Optimisation of Potent Antimalarial Quinazolinediones and Their Cytotoxicity against MCF-7

Quinazolinedione is one of the most outstanding heterocycles in medicinal chemistry thanks to its wide ranges of biological activities including antimalarial, anticancer, and anti-inflammatory. TCMDC-125133 containing a quinazolinedione pharmacophore displays promising antimalarial activity and low...

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Detalles Bibliográficos
Autores principales: Charoensutthivarakul, Sitthivut, Lohawittayanan, Duangporn, Kanjanasirirat, Phongthon, Jearawuttanakul, Kedchin, Seemakhan, Sawinee, Chabang, Napason, Schlaeppi, Patrick, Tantivess, Varisa, Limboonreung, Tanapol, Phanchana, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096129/
https://www.ncbi.nlm.nih.gov/pubmed/37049762
http://dx.doi.org/10.3390/molecules28072999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096129/
https://www.ncbi.nlm.nih.gov/pubmed/37049762
http://dx.doi.org/10.3390/molecules28072999

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