Combined action of albumin and heparin regulates lipoprotein lipase oligomerization, stability, and ligand interactions

Lipoprotein lipase (LPL), a crucial enzyme in the intravascular hydrolysis of triglyceride-rich lipoproteins, is a potential drug target for the treatment of hypertriglyceridemia. The activity and stability of LPL are influenced by a complex ligand network. Previous studies performed in dilute solut...

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Detalles Bibliográficos
Autores principales: Risti, Robert, Gunn, Kathryn H., Hiis-Hommuk, Kristofer, Seeba, Natjan-Naatan, Karimi, Hamed, Villo, Ly, Vendelin, Marko, Neher, Saskia B., Lõokene, Aivar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096250/
https://www.ncbi.nlm.nih.gov/pubmed/37043509
http://dx.doi.org/10.1371/journal.pone.0283358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096250/
https://www.ncbi.nlm.nih.gov/pubmed/37043509
http://dx.doi.org/10.1371/journal.pone.0283358

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