Activation of transcription factor CREB in human macrophages by Mycobacterium tuberculosis promotes bacterial survival, reduces NF-kB nuclear transit and limits phagolysosome fusion by reduced necroptotic signaling

Macrophages are a first line of defense against pathogens. However, certain invading microbes modify macrophage responses to promote their own survival and growth. Mycobacterium tuberculosis (M.tb) is a human-adapted intracellular pathogen that exploits macrophages as an intracellular niche. It was...

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Detalles Bibliográficos
Autores principales: Leopold Wager, Chrissy M., Bonifacio, Jordan R., Simper, Jan, Naoun, Adrian A., Arnett, Eusondia, Schlesinger, Larry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096260/
https://www.ncbi.nlm.nih.gov/pubmed/37000865
http://dx.doi.org/10.1371/journal.ppat.1011297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096260/
https://www.ncbi.nlm.nih.gov/pubmed/37000865
http://dx.doi.org/10.1371/journal.ppat.1011297

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