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An RNA-based system to study hepatitis B virus replication and evaluate antivirals

Hepatitis B virus (HBV) chronically infects an estimated 300 million people, and standard treatments are rarely curative. Infection increases the risk of liver cirrhosis and hepatocellular carcinoma, and consequently, nearly 1 million people die each year from chronic hepatitis B. Tools and approach...

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Detalles Bibliográficos
Autores principales: Yu, Yingpu, Schneider, William M., Kass, Maximilian A., Michailidis, Eleftherios, Acevedo, Ashley, Pamplona Mosimann, Ana L., Bordignon, Juliano, Koenig, Alexander, Livingston, Christine M., van Gijzel, Hardeep, Ni, Yi, Ambrose, Pradeep M., Freije, Catherine A., Zhang, Mengyin, Zou, Chenhui, Kabbani, Mohammad, Quirk, Corrine, Jahan, Cyprien, Wu, Xianfang, Urban, Stephan, You, Shihyun, Shlomai, Amir, de Jong, Ype P., Rice, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096565/
https://www.ncbi.nlm.nih.gov/pubmed/37043562
http://dx.doi.org/10.1126/sciadv.adg6265