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Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis

Metastasis is the main cause of death in many cancers including colorectal cancer (CRC); however, the underlying mechanisms responsible for metastatic progression remain largely unknown. We found that nuclear TYRO3 receptor tyrosine kinase is a strong predictor of poor overall survival in patients w...

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Detalles Bibliográficos
Autores principales: Hsu, Pei-Ling, Chien, Chun-Wei, Tang, Yen-An, Lin, Bo-Wen, Lin, Shih-Chieh, Lin, Yi-Syuan, Chen, Sih-Yu, Sun, H. Sunny, Tsai, Shaw-Jenq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096587/
https://www.ncbi.nlm.nih.gov/pubmed/37043564
http://dx.doi.org/10.1126/sciadv.ade3422