Evaluation of In Vivo Prepared Albumin-Drug Conjugate Using Immunoprecipitation Linked LC-MS Assay and Its Application to Mouse Pharmacokinetic Study

There have been many attempts in pharmaceutical industries and academia to improve the pharmacokinetic characteristics of anti-tumor small-molecule drugs by conjugating them with large molecules, such as monoclonal antibodies, called ADCs. In this context, albumin, one of the most abundant proteins...

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Detalles Bibliográficos
Autores principales: Lim, Jeong-Hyeon, Park, Minjae, Park, Yuri, Park, Seo-Jin, Lee, Jiyu, Hwang, Sangsoo, Lee, Jeongmin, Lee, Yujin, Jo, Eunjeong, Shin, Young G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096712/
https://www.ncbi.nlm.nih.gov/pubmed/37049985
http://dx.doi.org/10.3390/molecules28073223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096712/
https://www.ncbi.nlm.nih.gov/pubmed/37049985
http://dx.doi.org/10.3390/molecules28073223

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