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Evaluation of In Vivo Prepared Albumin-Drug Conjugate Using Immunoprecipitation Linked LC-MS Assay and Its Application to Mouse Pharmacokinetic Study

There have been many attempts in pharmaceutical industries and academia to improve the pharmacokinetic characteristics of anti-tumor small-molecule drugs by conjugating them with large molecules, such as monoclonal antibodies, called ADCs. In this context, albumin, one of the most abundant proteins...

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Detalles Bibliográficos
Autores principales:	Lim, Jeong-Hyeon, Park, Minjae, Park, Yuri, Park, Seo-Jin, Lee, Jiyu, Hwang, Sangsoo, Lee, Jeongmin, Lee, Yujin, Jo, Eunjeong, Shin, Young G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096712/ https://www.ncbi.nlm.nih.gov/pubmed/37049985 http://dx.doi.org/10.3390/molecules28073223

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