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Synthesis and Elimination Pathways of 1-Methanesulfonyl-1,2-dihydroquinoline Sulfonamides

A series of new Morita–Baylis–Hillman acetates were prepared and reacted with methanesulfonamide (K(2)CO(3), DMF, 23 °C) to produce tertiary dihydroquinoline sulfonamides in high yields. Subsequent efforts to eliminate the methylsulfonyl group from these derivatives (K(2)CO(3), DMF, 90 °C) as a rout...

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Detalles Bibliográficos
Autores principales: Ametsetor, Ebenezer, Fobi, Kwabena, Bunce, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10096818/
https://www.ncbi.nlm.nih.gov/pubmed/37050020
http://dx.doi.org/10.3390/molecules28073256