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Fingolimod ameliorates chronic experimental autoimmune neuritis by modulating inflammatory cytokines and Akt/mTOR/NF‐κB signaling

OBJECTIVE: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated disease that targets the myelin sheaths of the peripheral nerves. Fingolimod is a sphingosine 1 phosphate (S1P) receptor antagonist with a high affinity for S1P receptors through the Akt–mTOR pathway, a...

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Detalles Bibliográficos
Autores principales: Feng, Yuan, Feng, Fang, Pan, Shuyi, Zhang, Jiewen, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097075/
https://www.ncbi.nlm.nih.gov/pubmed/36917739
http://dx.doi.org/10.1002/brb3.2965