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Augmentation of BMP Signaling in Cranial Neural Crest Cells Leads to Premature Cranial Sutures Fusion through Endochondral Ossification in Mice

Craniosynostosis is a congenital anomaly characterized by the premature fusion of cranial sutures. Sutures are a critical connective tissue that regulates bone growth; their aberrant fusion results in abnormal shapes of the head and face. The molecular and cellular mechanisms have been investigated...

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Detalles Bibliográficos
Autores principales: Ueharu, Hiroki, Pan, Haichun, Liu, Xia, Ishii, Mamoru, Pongetti, Jessica, Kulkarni, Anshul K., Adegbenro, Folasade E., Wurn, Jaden, Maxson, Robert E., Sun, Hongchen, Komatsu, Yoshihiro, Zhang, Honghao, Yang, Jingwen, Mishina, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097634/
https://www.ncbi.nlm.nih.gov/pubmed/37065628
http://dx.doi.org/10.1002/jbm4.10716