Gene Therapy to Treat Osteopenia Associated With Chronic Ethanol Consumption and Aldehyde Dehydrogenase 2 Deficiency

Aldehyde dehydrogenase 2 (ALDH2) deficiency affects 35% to 45% of East Asians and 8% of the world population. ALDH2 is the second enzyme in the ethanol metabolism pathway. The common genetic variant ALDH2*2 allele has a glutamic acid‐to‐lysine substitution at position 487 (E487K) that reduces the en...

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Detalles Bibliográficos
Autores principales: Camilleri, Anna E, Cung, Michelle, Hart, Fiona M, Pagovich, Odelya E, Crystal, Ronald G, Greenblatt, Matthew B, Stiles, Katie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097638/
https://www.ncbi.nlm.nih.gov/pubmed/37065630
http://dx.doi.org/10.1002/jbm4.10723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097638/
https://www.ncbi.nlm.nih.gov/pubmed/37065630
http://dx.doi.org/10.1002/jbm4.10723

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