PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability

Spry2 is a molecular modulator of tyrosine kinase receptor signaling pathways that has cancer-type-specific effects. Mammalian Spry2 protein undergoes tyrosine and serine phosphorylation in response to growth factor stimulation. Spry2 expression is distinctly altered in various cancer types. Inhibit...

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Detalles Bibliográficos
Autores principales: Martínez, Natalia, Gragera, Teresa, de Lucas, María Pilar, Cámara, Ana Belén, Ballester, Alicia, Anta, Berta, Fernández-Medarde, Alberto, López-Briones, Tania, Ortega, Judith, Peña-Jiménez, Daniel, Barbáchano, Antonio, Montero-Calle, Ana, Cordero, Víctor, Barderas, Rodrigo, Iglesias, Teresa, Yunta, Mónica, Oliva, José Luís, Muñoz, Alberto, Santos, Eugenio, Zarich, Natasha, Rojas-Cabañeros, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097667/
https://www.ncbi.nlm.nih.gov/pubmed/37045830
http://dx.doi.org/10.1038/s41389-023-00465-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097667/
https://www.ncbi.nlm.nih.gov/pubmed/37045830
http://dx.doi.org/10.1038/s41389-023-00465-3

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