Flubendazole exhibits anti-glioblastoma effect by inhibiting STAT3 and promoting cell cycle arrest

Glioblastoma multiforme (GBM) belongs to most aggressive and invasive primary brain tumor in adults whose prognosis and survival remains poor. Potential new treatment modalities include targeting the cytoskeleton. In our study, we demonstrated that repurposed drug flubendazole (FLU) significantly in...

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Detalles Bibliográficos
Autores principales: Vítovcová, Barbora, Skarková, Veronika, Havelek, Radim, Soukup, Jiří, Pande, Ananya, Caltová, Kateřina, Rudolf, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097688/
https://www.ncbi.nlm.nih.gov/pubmed/37045903
http://dx.doi.org/10.1038/s41598-023-33047-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097688/
https://www.ncbi.nlm.nih.gov/pubmed/37045903
http://dx.doi.org/10.1038/s41598-023-33047-9

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