Sex difference in evolution of cognitive decline: studies on mouse model and the Dominantly Inherited Alzheimer Network cohort

Women carry a higher burden of Alzheimer’s disease (AD) compared to men, which is not accounted entirely by differences in lifespan. To identify the mechanisms underlying this effect, we investigated sex-specific differences in the progression of familial AD in humans and in APPswe/PS1ΔE9 mice. Acti...

Descripción completa

Detalles Bibliográficos
Autores principales: Kommaddi, Reddy Peera, Verma, Aditi, Muniz-Terrera, Graciela, Tiwari, Vivek, Chithanathan, Keerthana, Diwakar, Latha, Gowaikar, Ruturaj, Karunakaran, Smitha, Malo, Palash Kumar, Graff-Radford, Neill R., Day, Gregory S., Laske, Christoph, Vöglein, Jonathan, Nübling, Georg, Ikeuchi, Takeshi, Kasuga, Kensaku, Ravindranath, Vijayalakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097702/
https://www.ncbi.nlm.nih.gov/pubmed/37045867
http://dx.doi.org/10.1038/s41398-023-02411-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097702/
https://www.ncbi.nlm.nih.gov/pubmed/37045867
http://dx.doi.org/10.1038/s41398-023-02411-8

Ejemplares similares