DAXX drives de novo lipogenesis and contributes to tumorigenesis

Cancer cells exhibit elevated lipid synthesis. In breast and other cancer types, genes involved in lipid production are highly upregulated, but the mechanisms that control their expression remain poorly understood. Using integrated transcriptomic, lipidomic, and molecular studies, here we report tha...

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Detalles Bibliográficos
Autores principales: Mahmud, Iqbal, Tian, Guimei, Wang, Jia, Hutchinson, Tarun E., Kim, Brandon J., Awasthee, Nikee, Hale, Seth, Meng, Chengcheng, Moore, Allison, Zhao, Liming, Lewis, Jessica E., Waddell, Aaron, Wu, Shangtao, Steger, Julia M., Lydon, McKenzie L., Chait, Aaron, Zhao, Lisa Y., Ding, Haocheng, Li, Jian-Liang, Purayil, Hamsa Thayele, Huo, Zhiguang, Daaka, Yehia, Garrett, Timothy J., Liao, Daiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097704/
https://www.ncbi.nlm.nih.gov/pubmed/37045819
http://dx.doi.org/10.1038/s41467-023-37501-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097704/
https://www.ncbi.nlm.nih.gov/pubmed/37045819
http://dx.doi.org/10.1038/s41467-023-37501-0

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