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Anti-tumor effects of anti-programmed cell death-1 antibody treatment are attenuated in streptozotocin-induced diabetic mice

Hyperglycemia impairs immune response; however, it remains unknown whether the anti-tumor effects of anti-programmed cell death-1 antibody (PD-1-Ab) treatment are changed in hyperglycemic conditions. We analyzed the effect of PD-1-Ab on tumor growth in streptozotocin-induced diabetic mice (STZ-mice)...

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Detalles Bibliográficos
Autores principales: Ito, Masaaki, Iwama, Shintaro, Sugiyama, Daisuke, Yasuda, Yoshinori, Okuji, Takayuki, Kobayashi, Tomoko, Zhou, Xin, Yamagami, Ayana, Onoue, Takeshi, Miyata, Takashi, Sugiyama, Mariko, Hagiwara, Daisuke, Suga, Hidetaka, Banno, Ryoichi, Nishikawa, Hiroyoshi, Arima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097709/
https://www.ncbi.nlm.nih.gov/pubmed/37046033
http://dx.doi.org/10.1038/s41598-023-33049-7