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Contraction of the rigor actomyosin complex drives bulk hemoglobin expulsion from hemolyzing erythrocytes

Erythrocyte ghost formation via hemolysis is a key event in the physiological clearance of senescent red blood cells (RBCs) in the spleen. The turnover rate of millions of RBCs per second necessitates a rapid efflux of hemoglobin (Hb) from RBCs by a not yet identified mechanism. Using high-speed vid...

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Detalles Bibliográficos
Autores principales: Shirakashi, Ryo, Sisario, Dmitri, Taban, Danush, Korsa, Tessa, Wanner, Sophia B., Neubauer, Julia, Djuzenova, Cholpon S., Zimmermann, Heiko, Sukhorukov, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097772/
https://www.ncbi.nlm.nih.gov/pubmed/36357646
http://dx.doi.org/10.1007/s10237-022-01654-6