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Therapeutic effects of polydeoxyribonucleotide in an in vitro neuronal model of ischemia/reperfusion injury

Polydeoxyribonucleotide (PDRN) is an agonist that selectively stimulates adenosine A(2A) receptor (ADORA2A), which suppresses inflammatory responses. Ischemia/reperfusion (I/R) injury plays a major role in the pathogenesis of ischemic stroke by inducing neuroinflammation. Therefore, this study aimed...

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Detalles Bibliográficos
Autores principales: Jo, Seongmoon, Baek, Ahreum, Cho, Yoonhee, Kim, Sung Hoon, Baek, Dawoon, Hwang, Jihye, Cho, Sung-Rae, Kim, Hyun Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097812/
https://www.ncbi.nlm.nih.gov/pubmed/37045900
http://dx.doi.org/10.1038/s41598-023-32744-9