Warning regarding hematological toxicity of tamoxifen activated CreERT2 in young Rosa26CreERT2 mice

The Cre-lox system is a versatile and powerful tool used in mouse genetics. It allows spatial and/or temporal control of the deletion of a target gene. The Rosa26-CreERT2 (R26CreERT2) mouse model allows ubiquitous expression of CreERT2. Once activated by tamoxifen, CreERT2 will enter into the nuclei...

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Detalles Bibliográficos
Autores principales: Rossi, Martina, Salomon, Aude, Chaumontel, Nicolas, Molet, Jenny, Bailly, Sabine, Tillet, Emmanuelle, Bouvard, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097815/
https://www.ncbi.nlm.nih.gov/pubmed/37045870
http://dx.doi.org/10.1038/s41598-023-32633-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097815/
https://www.ncbi.nlm.nih.gov/pubmed/37045870
http://dx.doi.org/10.1038/s41598-023-32633-1

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