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Serum but not cerebrospinal fluid levels of allantoin are increased in de novo Parkinson’s disease

Oxidative stress supposedly plays a role in the pathogenesis of Parkinson’s disease (PD). Uric acid (UA), a powerful antioxidant, is lowered in PD while allantoin, the oxidation product of UA and known biomarker of oxidative stress, was not systematically studied in PD. We aim to compare serum and c...

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Detalles Bibliográficos
Autores principales: Hasíková, Lenka, Závada, Jakub, Serranová, Tereza, Kozlík, Petr, Kalíková, Květa, Kotačková, Lenka, Trnka, Jiří, Zogala, David, Šonka, Karel, Růžička, Evžen, Dušek, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097817/
https://www.ncbi.nlm.nih.gov/pubmed/37045835
http://dx.doi.org/10.1038/s41531-023-00505-0