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A maladaptive pleural environment suppresses preexisting anti-tumor activity of pleural infiltrating T cells

INTRODUCTION: Treatment options for patients with malignant pleural effusions (MPE) are limited due, at least in part, to the unique environment of the pleural space, which drives an aggressive tumor state and governs the behavior of infiltrating immune cells. Modulation of the pleural environment m...

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Detalles Bibliográficos
Autores principales: Donnenberg, Vera S., Luketich, James D., Sultan, Ibrahim, Lister, John, Bartlett, David L., Ghosh, Sohini, Donnenberg, Albert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097923/
https://www.ncbi.nlm.nih.gov/pubmed/37063842
http://dx.doi.org/10.3389/fimmu.2023.1157697