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Mechanosensitive mTORC1 signaling maintains lymphatic valves

Homeostatic maintenance and repair of lymphatic vessels are essential for health. We investigated the dynamics and the molecular mechanisms of lymphatic endothelial cell (LEC) renewal in adult mesenteric quiescent lymphatic vasculature using label-retention, lineage tracing, and cell ablation strate...

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Detalles Bibliográficos
Autores principales: Saygili Demir, Cansaran, Sabine, Amélie, Gong, Muyun, Dormond, Olivier, Petrova, Tatiana V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097975/
https://www.ncbi.nlm.nih.gov/pubmed/37036444
http://dx.doi.org/10.1083/jcb.202207049