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RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks

Replication fork reversal is an important mechanism to protect the stability of stalled forks and thereby preserve genomic integrity. While multiple enzymes have been identified that can remodel forks, their regulation remains poorly understood. Here, we demonstrate that the ubiquitin ligase RFWD3,...

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Detalles Bibliográficos
Autores principales: Moore, Chandler E., Yalcindag, Selin E., Czeladko, Hanna, Ravindranathan, Ramya, Wijesekara Hanthi, Yodhara, Levy, Juliana C., Sannino, Vincenzo, Schindler, Detlev, Ciccia, Alberto, Costanzo, Vincenzo, Elia, Andrew E.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097976/
https://www.ncbi.nlm.nih.gov/pubmed/37036693
http://dx.doi.org/10.1083/jcb.202106022