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RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks
Replication fork reversal is an important mechanism to protect the stability of stalled forks and thereby preserve genomic integrity. While multiple enzymes have been identified that can remodel forks, their regulation remains poorly understood. Here, we demonstrate that the ubiquitin ligase RFWD3,...
Autores principales: | Moore, Chandler E., Yalcindag, Selin E., Czeladko, Hanna, Ravindranathan, Ramya, Wijesekara Hanthi, Yodhara, Levy, Juliana C., Sannino, Vincenzo, Schindler, Detlev, Ciccia, Alberto, Costanzo, Vincenzo, Elia, Andrew E.H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10097976/ https://www.ncbi.nlm.nih.gov/pubmed/37036693 http://dx.doi.org/10.1083/jcb.202106022 |
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