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JNK/c‐Jun pathway activation is essential for HBx‐induced IL‐35 elevation to promote persistent HBV infection

BACKGROUND: Immunoregulation plays pivotal roles during chronic hepatitis B virus (HBV) infection. Studies have shown that Interleukin (IL)‐35 is an important molecule associated with inadequate immune response against HBV. However, the mechanisms involved in the up‐regulation of IL‐35 expression du...

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Detalles Bibliográficos
Autores principales: Li, Xuefen, Zhu, Qiaoyun, Ye, Bo, Zhu, Chunxia, Dong, Yuejiao, Ni, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098067/
https://www.ncbi.nlm.nih.gov/pubmed/36916737
http://dx.doi.org/10.1002/jcla.24860