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Autolysosomal exocytosis of lipids protect neurons from ferroptosis

During oxidative stress neurons release lipids that are internalized by glia. Defects in this coordinated process play an important role in several neurodegenerative diseases. Yet, the mechanisms of lipid release and its consequences on neuronal health are unclear. Here, we demonstrate that lipid-pr...

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Detalles Bibliográficos
Autores principales: Ralhan, Isha, Chang, Jinlan, Moulton, Matthew J., Goodman, Lindsey D., Lee, Nathanael Y.J., Plummer, Greg, Pasolli, H. Amalia, Matthies, Doreen, Bellen, Hugo J., Ioannou, Maria S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098143/
https://www.ncbi.nlm.nih.gov/pubmed/37036445
http://dx.doi.org/10.1083/jcb.202207130