Detection of microsatellite instability-high (MSI-H) by liquid biopsy predicts robust and durable response to immunotherapy in patients with pancreatic cancer

Clinical trials reporting the robust antitumor activity of immune checkpoint inhibitors (ICIs) in microsatellite instability-high (MSI-H) solid tumors have used tissue-based testing to determine the MSI-H status. This study assessed if MSI-H detected by a plasma-based circulating tumor DNA liquid bi...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Sakti, Bucheit, Leslie, Starr, Jason Scott, Innis-Shelton, Racquel, Shergill, Ardaman, Dada, Hiba, Resta, Regina, Wagner, Stephanie, Fei, Naomi, Kasi, Pashtoon Murtaza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098262/
https://www.ncbi.nlm.nih.gov/pubmed/35710297
http://dx.doi.org/10.1136/jitc-2021-004485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098262/
https://www.ncbi.nlm.nih.gov/pubmed/35710297
http://dx.doi.org/10.1136/jitc-2021-004485

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