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Effects of calreticulin mutations on cell transformation and immunity

Myeloproliferative neoplasms (MPNs) are cancers involving dysregulated production and function of myeloid lineage hematopoietic cells. Among MPNs, Essential thrombocythemia (ET), Polycythemia Vera (PV) and Myelofibrosis (MF), are driven by mutations that activate the JAK–STAT signalling pathway. Som...

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Detalles Bibliográficos
Autores principales: Desikan, Harini, Kaur, Amanpreet, Pogozheva, Irina D., Raghavan, Malini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098294/
https://www.ncbi.nlm.nih.gov/pubmed/36916035
http://dx.doi.org/10.1111/jcmm.17713