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Jagged/Notch proteins promote endothelial‐mesenchymal transition‐mediated pulmonary arterial hypertension via upregulation of the expression of GATAs

This study tested the hypothesis that Jagged2/Notches promoted the endothelial‐mesenchymal transition (endMT)‐mediated pulmonary arterial hypertension (PAH) (i.e. induction by monocrotaline [MCT]/63 mg/kg/subcutaneous injection) through increasing the expression of GATA‐binding factors which were in...

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Detalles Bibliográficos
Autores principales: Lin, Kun‐Chen, Yeh, Jui‐Ning, Shao, Pei‐Lin, Chiang, John Y., Sung, Pei‐Hsun, Huang, Chi‐Ruei, Chen, Yi‐Ling, Yip, Hon‐Kan, Guo, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098301/
https://www.ncbi.nlm.nih.gov/pubmed/36942326
http://dx.doi.org/10.1111/jcmm.17723