The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus

The protein high mobility group A1 (HMGA1) is an important regulator of chromatin organization and function. However, the mechanisms by which it exerts its biological function are not fully understood. Here, we report that the HMGA isoform, HMGA1a, nucleates into foci that display liquid‐like proper...

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Detalles Bibliográficos
Autores principales: Zhu, Hongjia, Narita, Masako, Joseph, Jerelle A., Krainer, Georg, Arter, William E., Olan, Ioana, Saar, Kadi L., Ermann, Niklas, Espinosa, Jorge R., Shen, Yi, Kuri, Masami Ando, Qi, Runzhang, Welsh, Timothy J., Collepardo‐Guevara, Rosana, Narita, Masashi, Knowles, Tuomas P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098602/
https://www.ncbi.nlm.nih.gov/pubmed/36336658
http://dx.doi.org/10.1002/cbic.202200450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098602/
https://www.ncbi.nlm.nih.gov/pubmed/36336658
http://dx.doi.org/10.1002/cbic.202200450

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