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The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus
The protein high mobility group A1 (HMGA1) is an important regulator of chromatin organization and function. However, the mechanisms by which it exerts its biological function are not fully understood. Here, we report that the HMGA isoform, HMGA1a, nucleates into foci that display liquid‐like proper...
Autores principales: | Zhu, Hongjia, Narita, Masako, Joseph, Jerelle A., Krainer, Georg, Arter, William E., Olan, Ioana, Saar, Kadi L., Ermann, Niklas, Espinosa, Jorge R., Shen, Yi, Kuri, Masami Ando, Qi, Runzhang, Welsh, Timothy J., Collepardo‐Guevara, Rosana, Narita, Masashi, Knowles, Tuomas P. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10098602/ https://www.ncbi.nlm.nih.gov/pubmed/36336658 http://dx.doi.org/10.1002/cbic.202200450 |
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